Human mAbs Broadly Protect against Arthritogenic Alphaviruses by Recognizing Conserved Elements of the Mxra8 Receptor-Binding Domain

Mosquito inoculation of humans with arthritogenic alphaviruses results in a febrile syndrome characterized by debilitating musculoskeletal pain and arthritis. Despite an expanding global disease burden, no approved therapies or licensed vaccines exist. Here, we describe human monoclonal antibodies (...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Host Microbe
Main Authors: Powell, Laura A., Miller, Andrew, Fox, Julie M., Kose, Nurgun, Klose, Thomas, Kim, Arthurs S., Bombardi, Robin, Tennekoon, Rashika N., de Silva, A. Dharshan, Carnahan, Robert H., Diamond, Michael S., Rossmann, Michael G., Kuhn, Richard J., Crowe, James E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7666055/
https://ncbi.nlm.nih.gov/pubmed/32783883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2020.07.008
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados