Expression of the Mxra8 Receptor Promotes Alphavirus Infection and Pathogenesis in Mice and Drosophila

Mxra8 is a recently described receptor for multiple alphaviruses, including Chikungunya (CHIKV), Mayaro (MAYV), Ross River (RRV), and O’nyong nyong (ONNV) viruses. To determine its role in pathogenesis, we generated mice with mutant Mxra8 alleles: an 8-nucleotide deletion that produces a truncated,...

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Publicado no:Cell Rep
Main Authors: Zhang, Rong, Earnest, James T., Kim, Arthur S., Winkler, Emma S., Desai, Pritesh, Adams, Lucas J., Hu, Gaowei, Bullock, Christopher, Gold, Beth, Cherry, Sara, Diamond, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6745702/
https://ncbi.nlm.nih.gov/pubmed/31484075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.07.105
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