Cryo-EM structure of Chikungunya virus in complex with the Mxra8 receptor

Mxra8 is a receptor for multiple arthritogenic alphaviruses that cause debilitating acute and chronic musculoskeletal disease in humans. Herein, we present a 2.2 Å resolution X-ray crystal structure of Mxra8 and 4 to 5 Å resolutioncryo-electron microscopy reconstructions of Mxra8 bound to chikunguny...

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Publié dans:Cell
Auteurs principaux: Basore, Katherine, Kim, Arthur S., Nelson, Christopher A., Zhang, Rong, Smith, Brittany K., Uranga, Carla, Vang, Lo, Cheng, Ming, Gross, Michael L., Smith, Jonathan, Diamond, Michael S., Fremont, Daved H.
Format: Artigo
Langue:Inglês
Publié: 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7227486/
https://ncbi.nlm.nih.gov/pubmed/31080061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.04.006
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