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Cryo-EM structure of Chikungunya virus in complex with the Mxra8 receptor
Mxra8 is a receptor for multiple arthritogenic alphaviruses that cause debilitating acute and chronic musculoskeletal disease in humans. Herein, we present a 2.2 Å resolution X-ray crystal structure of Mxra8 and 4 to 5 Å resolutioncryo-electron microscopy reconstructions of Mxra8 bound to chikunguny...
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| Udgivet i: | Cell |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7227486/ https://ncbi.nlm.nih.gov/pubmed/31080061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.04.006 |
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