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TRAF3IP3 mediates the recruitment of TRAF3 to MAVS for antiviral innate immunity
RIG‐I‐MAVS antiviral signaling represents an important pathway to stimulate interferon production and confer innate immunity to the host. Upon binding to viral RNA and Riplet‐mediated polyubiquitination, RIG‐I promotes prion‐like aggregation and activation of MAVS. MAVS subsequently induces interfer...
Guardat en:
| Publicat a: | EMBO J |
|---|---|
| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
John Wiley and Sons Inc.
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6745499/ https://ncbi.nlm.nih.gov/pubmed/31390091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019102075 |
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