TRAF3IP3 mediates the recruitment of TRAF3 to MAVS for antiviral innate immunity

RIG‐I‐MAVS antiviral signaling represents an important pathway to stimulate interferon production and confer innate immunity to the host. Upon binding to viral RNA and Riplet‐mediated polyubiquitination, RIG‐I promotes prion‐like aggregation and activation of MAVS. MAVS subsequently induces interfer...

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Udgivet i:EMBO J
Main Authors: Zhu, Wenting, Li, Jiaxin, Zhang, Rui, Cai, Yixiang, Wang, Changwan, Qi, Shishi, Chen, She, Liang, Xiaozhen, Qi, Nan, Hou, Fajian
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6745499/
https://ncbi.nlm.nih.gov/pubmed/31390091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019102075
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