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TRAF3IP3 mediates the recruitment of TRAF3 to MAVS for antiviral innate immunity

RIG‐I‐MAVS antiviral signaling represents an important pathway to stimulate interferon production and confer innate immunity to the host. Upon binding to viral RNA and Riplet‐mediated polyubiquitination, RIG‐I promotes prion‐like aggregation and activation of MAVS. MAVS subsequently induces interfer...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:EMBO J
Päätekijät: Zhu, Wenting, Li, Jiaxin, Zhang, Rui, Cai, Yixiang, Wang, Changwan, Qi, Shishi, Chen, She, Liang, Xiaozhen, Qi, Nan, Hou, Fajian
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6745499/
https://ncbi.nlm.nih.gov/pubmed/31390091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019102075
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