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Evidence for Internal Initiation of RNA Synthesis by the Hepatitis C Virus RNA-Dependent RNA Polymerase NS5B In Cellulo

Initiation of RNA synthesis by the hepatitis C virus (HCV) RNA-dependent RNA polymerase (RdRp) NS5B has been extensively studied in vitro and in cellulo. Intracellular replication is thought to rely exclusively on terminal de novo initiation, as it conserves all genetic information of the genome. In...

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Podrobná bibliografie
Vydáno v:J Virol
Hlavní autoři: Schult, Philipp, Nattermann, Maren, Lauber, Chris, Seitz, Stefan, Lohmann, Volker
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744235/
https://ncbi.nlm.nih.gov/pubmed/31315989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00525-19
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