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The F1 Motif of Dengue Virus Polymerase NS5 Is Involved in Promoter-Dependent RNA Synthesis

The mechanism by which viral RNA-dependent RNA polymerases (RdRp) specifically amplify viral genomes is still unclear. In the case of flaviviruses, a model has been proposed that involves the recognition of an RNA element present at the viral 5′ untranslated region, stem-loop A (SLA), that serves as...

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Autori principali: Iglesias, Nestor G., Filomatori, Claudia V., Gamarnik, Andrea V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126321/
https://ncbi.nlm.nih.gov/pubmed/21471248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02343-10
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