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Evidence for Internal Initiation of RNA Synthesis by the Hepatitis C Virus RNA-Dependent RNA Polymerase NS5B In Cellulo

Initiation of RNA synthesis by the hepatitis C virus (HCV) RNA-dependent RNA polymerase (RdRp) NS5B has been extensively studied in vitro and in cellulo. Intracellular replication is thought to rely exclusively on terminal de novo initiation, as it conserves all genetic information of the genome. In...

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Bibliografske podrobnosti
izdano v:J Virol
Main Authors: Schult, Philipp, Nattermann, Maren, Lauber, Chris, Seitz, Stefan, Lohmann, Volker
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744235/
https://ncbi.nlm.nih.gov/pubmed/31315989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00525-19
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