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Evidence for Internal Initiation of RNA Synthesis by the Hepatitis C Virus RNA-Dependent RNA Polymerase NS5B In Cellulo

Initiation of RNA synthesis by the hepatitis C virus (HCV) RNA-dependent RNA polymerase (RdRp) NS5B has been extensively studied in vitro and in cellulo. Intracellular replication is thought to rely exclusively on terminal de novo initiation, as it conserves all genetic information of the genome. In...

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Bibliografische gegevens
Gepubliceerd in:J Virol
Hoofdauteurs: Schult, Philipp, Nattermann, Maren, Lauber, Chris, Seitz, Stefan, Lohmann, Volker
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744235/
https://ncbi.nlm.nih.gov/pubmed/31315989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00525-19
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