Oncogene amplification in growth factor signaling pathways renders cancers dependent on membrane lipid remodeling

Advances in DNA sequencing technologies have reshaped our understanding of the molecular basis of cancer, providing a precise genomic view of tumors. Complementary biochemical and biophysical perspectives of cancer point towards profound shifts in nutrient uptake and utilization that propel tumor gr...

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Publicado en:Cell Metab
Main Authors: Bi, Junfeng, Ichu, Taka-Aki, Zanca, Ciro, Yang, Huijun, Zhang, Wei, Gu, Yuchao, Chowdhry, Sudhir, Reed, Alex, Ikegami, Shiro, Turner, Kristen M., Zhang, Wenjing, Villa, Genaro R., Wu, Sihan, Quehenberger, Oswald, Yong, William H., Kornblum, Harley I., Rich, Jeremy N., Cloughesy, Timothy F., Cavenee, Webster K., Furnari, Frank B., Cravatt, Benjamin F., Mischel, Paul S.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6742496/
https://ncbi.nlm.nih.gov/pubmed/31303424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2019.06.014
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