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Glucose-dependent acetylation of Rictor promotes targeted cancer therapy resistance
Cancer cells adapt their signaling in response to nutrient availability. To uncover the mechanisms regulating this process and its functional consequences, we interrogated cell lines, mouse tumor models, and clinical samples of glioblastoma (GBM), the highly lethal brain cancer. We discovered that g...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4522814/ https://ncbi.nlm.nih.gov/pubmed/26170313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1511759112 |
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