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Mechanical properties of tubulin intra- and inter-dimer interfaces and their implications for microtubule dynamic instability
Thirteen tubulin protofilaments, made of αβ-tubulin heterodimers, interact laterally to produce cytoskeletal microtubules. Microtubules exhibit the striking property of dynamic instability, manifested in their intermittent growth and shrinkage at both ends. This behavior is key to many cellular proc...
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| Опубликовано в: : | PLoS Comput Biol |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6742422/ https://ncbi.nlm.nih.gov/pubmed/31469822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007327 |
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