Molecular and Mechanical Causes of Microtubule Catastrophe and Aging

Tubulin polymers, microtubules, can switch abruptly from the assembly to shortening. These infrequent transitions, termed “catastrophes”, affect numerous cellular processes but the underlying mechanisms are elusive. We approached this complex stochastic system using advanced coarse-grained molecular...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Biophys J
Egile Nagusiak: Zakharov, Pavel, Gudimchuk, Nikita, Voevodin, Vladimir, Tikhonravov, Alexander, Ataullakhanov, Fazoil I., Grishchuk, Ekaterina L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Biophysical Society 2015
Gaiak:
Molecular Machines, Motors, and Nanoscale Biophysics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701015/
https://ncbi.nlm.nih.gov/pubmed/26682815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.10.048
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