Mechanical properties of tubulin intra- and inter-dimer interfaces and their implications for microtubule dynamic instability

Thirteen tubulin protofilaments, made of αβ-tubulin heterodimers, interact laterally to produce cytoskeletal microtubules. Microtubules exhibit the striking property of dynamic instability, manifested in their intermittent growth and shrinkage at both ends. This behavior is key to many cellular proc...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Fedorov, Vladimir A., Orekhov, Philipp S., Kholina, Ekaterina G., Zhmurov, Artem A., Ataullakhanov, Fazoil I., Kovalenko, Ilya B., Gudimchuk, Nikita B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6742422/
https://ncbi.nlm.nih.gov/pubmed/31469822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007327
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