Mechanical properties of tubulin intra- and inter-dimer interfaces and their implications for microtubule dynamic instability

Thirteen tubulin protofilaments, made of αβ-tubulin heterodimers, interact laterally to produce cytoskeletal microtubules. Microtubules exhibit the striking property of dynamic instability, manifested in their intermittent growth and shrinkage at both ends. This behavior is key to many cellular proc...

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Dettagli Bibliografici
Pubblicato in:PLoS Comput Biol
Autori principali: Fedorov, Vladimir A., Orekhov, Philipp S., Kholina, Ekaterina G., Zhmurov, Artem A., Ataullakhanov, Fazoil I., Kovalenko, Ilya B., Gudimchuk, Nikita B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6742422/
https://ncbi.nlm.nih.gov/pubmed/31469822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007327
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