Mechanical properties of tubulin intra- and inter-dimer interfaces and their implications for microtubule dynamic instability

Thirteen tubulin protofilaments, made of αβ-tubulin heterodimers, interact laterally to produce cytoskeletal microtubules. Microtubules exhibit the striking property of dynamic instability, manifested in their intermittent growth and shrinkage at both ends. This behavior is key to many cellular proc...

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Bibliografske podrobnosti
izdano v:PLoS Comput Biol
Main Authors: Fedorov, Vladimir A., Orekhov, Philipp S., Kholina, Ekaterina G., Zhmurov, Artem A., Ataullakhanov, Fazoil I., Kovalenko, Ilya B., Gudimchuk, Nikita B.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2019
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6742422/
https://ncbi.nlm.nih.gov/pubmed/31469822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007327
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