Mechanical properties of tubulin intra- and inter-dimer interfaces and their implications for microtubule dynamic instability

Thirteen tubulin protofilaments, made of αβ-tubulin heterodimers, interact laterally to produce cytoskeletal microtubules. Microtubules exhibit the striking property of dynamic instability, manifested in their intermittent growth and shrinkage at both ends. This behavior is key to many cellular proc...

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Bibliografski detalji
Izdano u:PLoS Comput Biol
Glavni autori: Fedorov, Vladimir A., Orekhov, Philipp S., Kholina, Ekaterina G., Zhmurov, Artem A., Ataullakhanov, Fazoil I., Kovalenko, Ilya B., Gudimchuk, Nikita B.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2019
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6742422/
https://ncbi.nlm.nih.gov/pubmed/31469822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007327
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