Microtubules grow by the addition of bent guanosine triphosphate tubulin to the tips of curved protofilaments

We used electron tomography to examine microtubules (MTs) growing from pure tubulin in vitro as well as two classes of MTs growing in cells from six species. The tips of all these growing MTs display bent protofilaments (PFs) that curve away from the MT axis, in contrast with previously reported MTs...

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Publicado en:J Cell Biol
Autores principales: McIntosh, J. Richard, O’Toole, Eileen, Morgan, Garry, Austin, Jotham, Ulyanov, Evgeniy, Ataullakhanov, Fazoil, Gudimchuk, Nikita
Formato: Artigo
Lenguaje:Inglês
Publicado: Rockefeller University Press 2018
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Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6080942/
https://ncbi.nlm.nih.gov/pubmed/29794031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201802138
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