Microtubules grow by the addition of bent guanosine triphosphate tubulin to the tips of curved protofilaments

We used electron tomography to examine microtubules (MTs) growing from pure tubulin in vitro as well as two classes of MTs growing in cells from six species. The tips of all these growing MTs display bent protofilaments (PFs) that curve away from the MT axis, in contrast with previously reported MTs...

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Bibliografische gegevens
Gepubliceerd in:J Cell Biol
Hoofdauteurs: McIntosh, J. Richard, O’Toole, Eileen, Morgan, Garry, Austin, Jotham, Ulyanov, Evgeniy, Ataullakhanov, Fazoil, Gudimchuk, Nikita
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Rockefeller University Press 2018
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6080942/
https://ncbi.nlm.nih.gov/pubmed/29794031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201802138
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