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Microtubules grow by the addition of bent guanosine triphosphate tubulin to the tips of curved protofilaments

We used electron tomography to examine microtubules (MTs) growing from pure tubulin in vitro as well as two classes of MTs growing in cells from six species. The tips of all these growing MTs display bent protofilaments (PFs) that curve away from the MT axis, in contrast with previously reported MTs...

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書目詳細資料
發表在:J Cell Biol
Main Authors: McIntosh, J. Richard, O’Toole, Eileen, Morgan, Garry, Austin, Jotham, Ulyanov, Evgeniy, Ataullakhanov, Fazoil, Gudimchuk, Nikita
格式: Artigo
語言:Inglês
出版: Rockefeller University Press 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6080942/
https://ncbi.nlm.nih.gov/pubmed/29794031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201802138
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