Microtubules grow by the addition of bent guanosine triphosphate tubulin to the tips of curved protofilaments

We used electron tomography to examine microtubules (MTs) growing from pure tubulin in vitro as well as two classes of MTs growing in cells from six species. The tips of all these growing MTs display bent protofilaments (PFs) that curve away from the MT axis, in contrast with previously reported MTs...

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Библиографические подробности
Опубликовано в: :J Cell Biol
Главные авторы: McIntosh, J. Richard, O’Toole, Eileen, Morgan, Garry, Austin, Jotham, Ulyanov, Evgeniy, Ataullakhanov, Fazoil, Gudimchuk, Nikita
Формат: Artigo
Язык:Inglês
Опубликовано: Rockefeller University Press 2018
Предметы:
Research Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6080942/
https://ncbi.nlm.nih.gov/pubmed/29794031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201802138
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