Molecular and Mechanical Causes of Microtubule Catastrophe and Aging

Tubulin polymers, microtubules, can switch abruptly from the assembly to shortening. These infrequent transitions, termed “catastrophes”, affect numerous cellular processes but the underlying mechanisms are elusive. We approached this complex stochastic system using advanced coarse-grained molecular...

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Vydáno v:Biophys J
Hlavní autoři: Zakharov, Pavel, Gudimchuk, Nikita, Voevodin, Vladimir, Tikhonravov, Alexander, Ataullakhanov, Fazoil I., Grishchuk, Ekaterina L.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2015
Témata:
Molecular Machines, Motors, and Nanoscale Biophysics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701015/
https://ncbi.nlm.nih.gov/pubmed/26682815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.10.048
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