Molecular and Mechanical Causes of Microtubule Catastrophe and Aging

Tubulin polymers, microtubules, can switch abruptly from the assembly to shortening. These infrequent transitions, termed “catastrophes”, affect numerous cellular processes but the underlying mechanisms are elusive. We approached this complex stochastic system using advanced coarse-grained molecular...

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Detalles Bibliográficos
Publicado en:Biophys J
Autores principales: Zakharov, Pavel, Gudimchuk, Nikita, Voevodin, Vladimir, Tikhonravov, Alexander, Ataullakhanov, Fazoil I., Grishchuk, Ekaterina L.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Biophysical Society 2015
Materias:
Molecular Machines, Motors, and Nanoscale Biophysics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701015/
https://ncbi.nlm.nih.gov/pubmed/26682815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.10.048
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