Intravitreal Gene Therapy Reduces Lysosomal Storage in Specific Areas of the CNS in Mucopolysaccharidosis VII Mice

The mucopolysaccharidoses (MPSs) are lysosomal storage diseases resulting from impaired catabolism of sulfated glycosaminoglycans. MPS VII mice lack lysosomal β-glucuronidase (GUSB) activity, leading to the accumulation of partially degraded chondroitin, dermatan, and heparan sulfates in most tissue...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Hennig, Anne K., Levy, Beth, Ogilvie, Judith Mosinger, Vogler, Carole A., Galvin, Nancy, Bassnett, Steven, Sands, Mark S.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2003
Assuntos:
ARTICLE
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6742327/
https://ncbi.nlm.nih.gov/pubmed/12716937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-08-03302.2003
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares