Enzyme replacement therapy for murine mucopolysaccharidosis type VII.

Recombinant mouse beta-glucuronidase administered intravenously to newborn mice with mucopolysaccharidosis type VII (MPS VII) is rapidly cleared from the circulation and localized in many tissues. Here we determine the tissue distribution of injected enzyme and describe its effects on the histopatho...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Clin Invest
Main Authors: Sands, M S, Vogler, C, Kyle, J W, Grubb, J H, Levy, B, Galvin, N, Sly, W S, Birkenmeier, E H
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 1994
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294437/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8200966/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117237
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