Intracisternal A-Particle Element Transposition into the Murine β-Glucuronidase Gene Correlates with Loss of Enzyme Activity: a New Model for β-Glucuronidase Deficiency in the C3H Mouse

The severity of human mucopolysaccharidosis type VII (MPS VII), or Sly syndrome, depends on the relative activity of the enzyme β-glucuronidase. Loss of β-glucuronidase activity can cause hydrops fetalis, with in utero or postnatal death of the patient. In this report, we show that β-glucuronidase a...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Gwynn, Babette, Lueders, Kira, Sands, Mark S., Birkenmeier, Edward H.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1998
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109233/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9774663/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.11.6474
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