Correction of murine mucopolysaccharidosis VII by a human beta-glucuronidase transgene.

We recently described a murine model for mucopolysaccharidosis VII in mice that have an inherited deficiency of beta-glucuronidase (beta-D-glucuronoside glucuronosohydrolase, EC 3.2.1.31). Affected mice, of genotype gusmps/gusmps, present clinical manifestations similar to those of humans with mucop...

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Main Authors: Kyle, J W, Birkenmeier, E H, Gwynn, B, Vogler, C, Hoppe, P C, Hoffmann, J W, Sly, W S
Formato: Artigo
Idioma:Inglês
Publicado: 1990
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC54014/
https://ncbi.nlm.nih.gov/pubmed/2111021
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