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Correction of murine mucopolysaccharidosis VII by a human beta-glucuronidase transgene.

We recently described a murine model for mucopolysaccharidosis VII in mice that have an inherited deficiency of beta-glucuronidase (beta-D-glucuronoside glucuronosohydrolase, EC 3.2.1.31). Affected mice, of genotype gusmps/gusmps, present clinical manifestations similar to those of humans with mucop...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Kyle, J W, Birkenmeier, E H, Gwynn, B, Vogler, C, Hoppe, P C, Hoffmann, J W, Sly, W S
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1990
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54014/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2111021/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.10.3914
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