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Enzyme replacement therapy for murine mucopolysaccharidosis type VII.

Recombinant mouse beta-glucuronidase administered intravenously to newborn mice with mucopolysaccharidosis type VII (MPS VII) is rapidly cleared from the circulation and localized in many tissues. Here we determine the tissue distribution of injected enzyme and describe its effects on the histopatho...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Principais autores: Sands, M S, Vogler, C, Kyle, J W, Grubb, J H, Levy, B, Galvin, N, Sly, W S, Birkenmeier, E H
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1994
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294437/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8200966/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117237
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