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Murine mucopolysaccharidosis type VII. Characterization of a mouse with beta-glucuronidase deficiency.

We have characterized a new mutant mouse that has virtually no beta-glucuronidase activity. This biochemical defect causes a murine lysosomal storage disease that has many interesting similarities to human mucopolysaccharidosis type VII (MPS VII; Sly syndrome; beta-glucuronidase deficiency). Genetic...

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Main Authors: Birkenmeier, E H, Davisson, M T, Beamer, W G, Ganschow, R E, Vogler, C A, Gwynn, B, Lyford, K A, Maltais, L M, Wawrzyniak, C J
格式: Artigo
語言:Inglês
出版: 1989
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC303816/
https://ncbi.nlm.nih.gov/pubmed/2495302
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