A murine model of mucopolysaccharidosis VII. Gross and microscopic findings in beta-glucuronidase-deficient mice.

This report describes the clinical and pathologic alterations found in mice that have a recessively inherited, essentially complete deficiency of the lysosomal enzyme beta-glucuronidase. Affected animals have a shortened life span and are dysmorphic and dwarfed. Abnormal gait and decreased joint mob...

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Autori principali: Vogler, C., Birkenmeier, E. H., Sly, W. S., Levy, B., Pegors, C., Kyle, J. W., Beamer, W. G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1990
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1877452/
https://ncbi.nlm.nih.gov/pubmed/2105058
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