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Enzyme replacement therapy for murine mucopolysaccharidosis type VII.

Recombinant mouse beta-glucuronidase administered intravenously to newborn mice with mucopolysaccharidosis type VII (MPS VII) is rapidly cleared from the circulation and localized in many tissues. Here we determine the tissue distribution of injected enzyme and describe its effects on the histopatho...

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Publicado no:J Clin Invest
Principais autores: Sands, M S, Vogler, C, Kyle, J W, Grubb, J H, Levy, B, Galvin, N, Sly, W S, Birkenmeier, E H
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294437/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8200966/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117237
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