Enzyme replacement therapy for murine mucopolysaccharidosis type VII.

Recombinant mouse beta-glucuronidase administered intravenously to newborn mice with mucopolysaccharidosis type VII (MPS VII) is rapidly cleared from the circulation and localized in many tissues. Here we determine the tissue distribution of injected enzyme and describe its effects on the histopatho...

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Bibliografische gegevens
Gepubliceerd in:J Clin Invest
Hoofdauteurs: Sands, M S, Vogler, C, Kyle, J W, Grubb, J H, Levy, B, Galvin, N, Sly, W S, Birkenmeier, E H
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 1994
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Research Article
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294437/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8200966/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117237
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