Prostaglandin E(2) Activates the Histaminergic System via the EP(4) Receptor to Induce Wakefulness in Rats

Prostaglandin (PG)E(2) promotes the wakeful state when administered into the posterior hypothalamus, in which the histaminergic tuberomammillary nucleus (TMN) is located. To explore the neurotransmitter mechanisms responsible for PGE(2)-induced wakefulness in rats, we examined the effect of PGE(2) o...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Huang, Zhi-Li, Sato, Yo, Mochizuki, Takatoshi, Okada, Tetsuya, Qu, Wei-Min, Yamatodani, Atsushi, Urade, Yoshihiro, Hayaishi, Osamu
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2003
Assuntos:
Behavioral/Systems/Cognitive
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740344/
https://ncbi.nlm.nih.gov/pubmed/12853415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-14-05975.2003
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