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Prostaglandin E(2) Activates the Histaminergic System via the EP(4) Receptor to Induce Wakefulness in Rats

Prostaglandin (PG)E(2) promotes the wakeful state when administered into the posterior hypothalamus, in which the histaminergic tuberomammillary nucleus (TMN) is located. To explore the neurotransmitter mechanisms responsible for PGE(2)-induced wakefulness in rats, we examined the effect of PGE(2) o...

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Bibliografske podrobnosti
izdano v:J Neurosci
Main Authors: Huang, Zhi-Li, Sato, Yo, Mochizuki, Takatoshi, Okada, Tetsuya, Qu, Wei-Min, Yamatodani, Atsushi, Urade, Yoshihiro, Hayaishi, Osamu
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2003
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740344/
https://ncbi.nlm.nih.gov/pubmed/12853415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-14-05975.2003
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