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Adenosine in the tuberomammillary nucleus inhibits the histaminergic system via A(1) receptors and promotes non-rapid eye movement sleep

Adenosine has been proposed to promote sleep through A(1) receptors (A(1)R's) and/or A(2A) receptors in the brain. We previously reported that A(2A) receptors mediate the sleep-promoting effect of prostaglandin D(2), an endogenous sleep-inducing substance, and that activation of these receptors...

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Détails bibliographiques
Auteurs principaux: Oishi, Yo, Huang, Zhi-Li, Fredholm, Bertil B., Urade, Yoshihiro, Hayaishi, Osamu
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2604968/
https://ncbi.nlm.nih.gov/pubmed/19066225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810926105
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