Effects of Lesions of the Histaminergic Tuberomammillary Nucleus on Spontaneous Sleep in Rats

STUDY OBJECTIVES: Extensive evidence suggests that histaminergic neurons promote wakefulness. Histaminergic neurons are found exclusively in the tuberomammillary nucleus (TMN), and electrolytic lesions of the posterior hypothalamus, where the TMN resides, produce intense hypersomnolence. However, el...

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Main Authors: Gerashchenko, Dmitry, Chou, Thomas C., Blanco-Centurion, Carlos A., Saper, Clifford B., Shiromani, Priyattam J.
Format: Artigo
Language:Inglês
Published: 2004
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1249486/
https://ncbi.nlm.nih.gov/pubmed/15586780
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