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Prostaglandin D synthase gene is involved in the regulation of non-rapid eye movement sleep

To examine the function of prostaglandin (PG) D synthase (PGDS) gene, as well as endogenously produced PGD(2) in sleep regulation in vivo, we generated transgenic (TG) mice that overexpress human PGDS gene to study their sleep behavior. Although no difference was observed in the sleep/wake patterns...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Pinzar, Elena, Kanaoka, Yoshihide, Inui, Takashi, Eguchi, Naomi, Urade, Yoshihiro, Hayaishi, Osamu
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2000
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18330/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10781097/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.090093997
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