Biochemical and Structural Characteristics, Gene Regulation, Physiological, Pathological and Clinical Features of Lipocalin-Type Prostaglandin D2 Synthase as a Multifunctional Lipocalin
Lipocalin-type prostaglandin (PG) D2 synthase (L-PGDS) catalyzes the isomerization of PGH2, a common precursor of the two series of PGs, to produce PGD2. PGD2 stimulates three distinct types of G protein-coupled receptors: (1) D type of prostanoid (DP) receptors involved in the regulation of sleep,...
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| Formato: | Artigo |
| Lenguaje: | Inglês |
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Frontiers Media S.A.
2021-10-01
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| Colección: | Frontiers in Physiology |
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| Acceso en línea: | https://www.frontiersin.org/articles/10.3389/fphys.2021.718002/full |
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