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Prostaglandin D synthase gene is involved in the regulation of non-rapid eye movement sleep

To examine the function of prostaglandin (PG) D synthase (PGDS) gene, as well as endogenously produced PGD(2) in sleep regulation in vivo, we generated transgenic (TG) mice that overexpress human PGDS gene to study their sleep behavior. Although no difference was observed in the sleep/wake patterns...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Pinzar, Elena, Kanaoka, Yoshihide, Inui, Takashi, Eguchi, Naomi, Urade, Yoshihiro, Hayaishi, Osamu
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18330/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10781097/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.090093997
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