Prostaglandin D synthase gene is involved in the regulation of non-rapid eye movement sleep

To examine the function of prostaglandin (PG) D synthase (PGDS) gene, as well as endogenously produced PGD(2) in sleep regulation in vivo, we generated transgenic (TG) mice that overexpress human PGDS gene to study their sleep behavior. Although no difference was observed in the sleep/wake patterns...

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Bibliographic Details
Main Authors: Pinzar, Elena, Kanaoka, Yoshihide, Inui, Takashi, Eguchi, Naomi, Urade, Yoshihiro, Hayaishi, Osamu
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2000
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC18330/
https://ncbi.nlm.nih.gov/pubmed/10781097
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