Prostaglandin E(2) Activates the Histaminergic System via the EP(4) Receptor to Induce Wakefulness in Rats

Prostaglandin (PG)E(2) promotes the wakeful state when administered into the posterior hypothalamus, in which the histaminergic tuberomammillary nucleus (TMN) is located. To explore the neurotransmitter mechanisms responsible for PGE(2)-induced wakefulness in rats, we examined the effect of PGE(2) o...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Huang, Zhi-Li, Sato, Yo, Mochizuki, Takatoshi, Okada, Tetsuya, Qu, Wei-Min, Yamatodani, Atsushi, Urade, Yoshihiro, Hayaishi, Osamu
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2003
Fag:
Behavioral/Systems/Cognitive
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740344/
https://ncbi.nlm.nih.gov/pubmed/12853415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-14-05975.2003
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