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Arousal effect of orexin A depends on activation of the histaminergic system

Orexin neurons are exclusively localized in the lateral hypothalamic area and project their fibers to the entire central nervous system, including the histaminergic tuberomammillary nucleus (TMN). Dysfunction of the orexin system results in the sleep disorder narcolepsy, but the role of orexin in ph...

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Detalhes bibliográficos
Main Authors: Huang, Zhi-Li, Qu, Wei-Min, Li, Wei-Dong, Mochizuki, Takatoshi, Eguchi, Naomi, Watanabe, Takeshi, Urade, Yoshihiro, Hayaishi, Osamu
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC55561/
https://ncbi.nlm.nih.gov/pubmed/11493714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.181330998
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