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Altered sleep–wake characteristics and lack of arousal response to H(3) receptor antagonist in histamine H(1) receptor knockout mice

Histaminergic neurons play an important role in the regulation of sleep–wake behavior through histamine H(1) receptors (H(1)R). Blockade of the histamine H(3) receptor (H(3)R) is proposed to induce wakefulness by regulating the release of various wake-related transmitters, not only histamine. In the...

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Autori principali: Huang, Zhi-Li, Mochizuki, Takatoshi, Qu, Wei-Min, Hong, Zong-Yuan, Watanabe, Takeshi, Urade, Yoshihiro, Hayaishi, Osamu
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1450232/
https://ncbi.nlm.nih.gov/pubmed/16537376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600451103
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