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Geometric considerations support the double‐displacement catalytic mechanism of l‐asparaginase

Twenty crystal structures of the complexes of l‐asparaginase with l‐Asn, l‐Asp, and succinic acid that are currently available in the Protein Data Bank, as well as 11 additional structures determined in the course of this project, were analyzed in order to establish the level of conservation of the...

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Библиографические подробности
Опубликовано в: :Protein Sci
Главные авторы: Lubkowski, Jacek, Wlodawer, Alexander
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley & Sons, Inc. 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740147/
https://ncbi.nlm.nih.gov/pubmed/31423681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3709
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