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Geometric considerations support the double‐displacement catalytic mechanism of l‐asparaginase

Twenty crystal structures of the complexes of l‐asparaginase with l‐Asn, l‐Asp, and succinic acid that are currently available in the Protein Data Bank, as well as 11 additional structures determined in the course of this project, were analyzed in order to establish the level of conservation of the...

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Dettagli Bibliografici
Pubblicato in:Protein Sci
Autori principali: Lubkowski, Jacek, Wlodawer, Alexander
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons, Inc. 2019
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740147/
https://ncbi.nlm.nih.gov/pubmed/31423681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3709
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