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Opportunistic complexes of E. coli L-asparaginases with citrate anions

Active sites of enzymes are highly optimized for interactions with specific substrates, thus binding of opportunistic ligands is usually observed only in the absence of native substrates or products. However, during growth of crystals required for structure determination enzymes are often exposed to...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lubkowski, Jacek, Chan, Waikin, Wlodawer, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6667453/
https://ncbi.nlm.nih.gov/pubmed/31363102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46432-0
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