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Geometric considerations support the double‐displacement catalytic mechanism of l‐asparaginase

Twenty crystal structures of the complexes of l‐asparaginase with l‐Asn, l‐Asp, and succinic acid that are currently available in the Protein Data Bank, as well as 11 additional structures determined in the course of this project, were analyzed in order to establish the level of conservation of the...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Lubkowski, Jacek, Wlodawer, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740147/
https://ncbi.nlm.nih.gov/pubmed/31423681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3709
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