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Generalized enzymatic mechanism of catalysis by tetrameric l-asparaginases from mesophilic bacteria
The mechanism of catalysis by the l-glutaminase-asparaginase from Pseudomonas 7A (PGA) was investigated using structural, mass spectrometry, and kinetic data. We had previously proposed mechanism of hydrolysis of l-Asn by the type II l-asparaginase from E. coli (EcAII), but that work was limited to...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7567106/ https://ncbi.nlm.nih.gov/pubmed/33060684 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74480-4 |
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