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Crystal structure of a complex of the intracellular domain of interferon λ receptor 1 (IFNLR1) and the FERM/SH2 domains of human JAK1

The crystal structure of a construct consisting of the FERM and SH2-like domains of the human Janus kinase 1 (JAK1) bound to a fragment of the intracellular domain of the interferon λ receptor 1 (IFNLR1) has been determined at the nominal resolution of 2.1 Å. In this structure the receptor peptide f...

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Publicado en:J Mol Biol
Main Authors: Zhang, Di, Wlodawer, Alexander, Lubkowski, Jacek
Formato: Artigo
Idioma:Inglês
Publicado: 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6288811/
https://ncbi.nlm.nih.gov/pubmed/27725180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2016.10.005
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