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The Janus Kinase (JAK) FERM and SH2 Domains: Bringing Specificity to JAK–Receptor Interactions

The Janus kinases (JAKs) are non-receptor tyrosine kinases essential for signaling in response to cytokines and interferons and thereby control many essential functions in growth, development, and immune regulation. JAKs are unique among tyrosine kinases for their constitutive yet non-covalent assoc...

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Bibliografski detalji
Izdano u:Front Endocrinol (Lausanne)
Glavni autori: Ferrao, Ryan, Lupardus, Patrick J.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5394478/
https://ncbi.nlm.nih.gov/pubmed/28458652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2017.00071
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