Crystal structure of Escherichia coli L-asparaginase, an enzyme used in cancer therapy.

The crystal structure of Escherichia coli asparaginase II (EC 3.5.1.1), a drug (Elspar) used for the treatment of acute lymphoblastic leukemia, has been determined at 2.3 A resolution by using data from a single heavy atom derivative in combination with molecular replacement. The atomic model was re...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Swain, A L, Jaskólski, M, Housset, D, Rao, J K, Wlodawer, A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45896/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8434007/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.4.1474
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