Crystal structure of Escherichia coli L-asparaginase, an enzyme used in cancer therapy.
The crystal structure of Escherichia coli asparaginase II (EC 3.5.1.1), a drug (Elspar) used for the treatment of acute lymphoblastic leukemia, has been determined at 2.3 A resolution by using data from a single heavy atom derivative in combination with molecular replacement. The atomic model was re...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1993
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45896/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8434007/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.4.1474 |
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