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Opportunistic complexes of E. coli L-asparaginases with citrate anions

Active sites of enzymes are highly optimized for interactions with specific substrates, thus binding of opportunistic ligands is usually observed only in the absence of native substrates or products. However, during growth of crystals required for structure determination enzymes are often exposed to...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Lubkowski, Jacek, Chan, Waikin, Wlodawer, Alexander
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6667453/
https://ncbi.nlm.nih.gov/pubmed/31363102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46432-0
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