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Reshuffling yeast chromosomes with CRISPR/Cas9
Genome engineering is a powerful approach to study how chromosomal architecture impacts phenotypes. However, quantifying the fitness impact of translocations independently from the confounding effect of base substitutions has so far remained challenging. We report a novel application of the CRISPR/C...
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| 出版年: | PLoS Genet |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6738639/ https://ncbi.nlm.nih.gov/pubmed/31465441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008332 |
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