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Reshuffling yeast chromosomes with CRISPR/Cas9
Genome engineering is a powerful approach to study how chromosomal architecture impacts phenotypes. However, quantifying the fitness impact of translocations independently from the confounding effect of base substitutions has so far remained challenging. We report a novel application of the CRISPR/C...
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| Publicado en: | PLoS Genet |
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| Autores principales: | , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6738639/ https://ncbi.nlm.nih.gov/pubmed/31465441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008332 |
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